Medical Doctor Of Internal Medicine

[GGMicefleedgilI]

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Serious adverse events, although infrequent, include seizures, gallstones (due to rapid weight loss), glaucoma and manic episodes in bipolar patients.
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The benefits (reduced risks of obesity, improvements in glycemic control, hyperlipidemia) and the risks (especially cardiovascular adverse effects) of sibutramine therapy must be discussed with patients together with alternative and complementary measures such as diet, exercise and lifestyle modification.
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Meridia does not appear to cause cardiac valve disease, maybe because it does not cause serotonin release.