BioMarin's cancer drug success prompts launch of pivotal trial

[riky]

BioMarin's cancer drug success prompts launch of pivotal trial

(Reuters) - An experimental cancer drug from BioMarin Pharmaceutical Inc has proven to be effective in treating patients with breast or ovarian cancers caused by mutation in the BRCA gene that repairs damaged DNA, early data show. The drug, BMN673, is part of a new class known as PARP inhibitors. PARP, or poly ADP ribose polymerase, is an enzyme used by the body to repair broken DNA that can also be used by cancer cells to survive. By blocking PARP, drugmakers hope to prevent cancer cells from spreading. ...

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