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Posted by wlsqfjaru
 - March 09, 2011, 09:22:10 AM
Diabetes with hyperlipidemia rational drug use
 
 
Hypersensitivity to any component of this product are women of childbearing age, pregnant or lactating women, can not be used in patients with active liver disease. 1.2 Anion Exchange on behalf of the tree class of drug test meal to enamine (cholestyramine) and test to back parking. Mainly in the intestinal bile acid resistance in Taiwan, Sri Lanka end its enterohepatic circulation, the liver cholesterol compensatory synthesis of new bile acid, thereby depleting reserves of liver cholesterol and increase LDL from the blood absorption rate. Cholesterol can reduce the increase% ~ 30%, HDL increased 5% to 10%. Therefore, for HDL cholesterol and reduce patients. The main side effects are ignorant of the poor and constipation, flavoring agents can be used to increase dietary fiber to reduce the orderly. Because there are different degrees of resin increased the role of rig,You are not allowed to view links. Register or Login, it simply does not apply to diabetes, hyperlipidemia rig or platform and in the high threshold are. 1.3 {probucol probucol acid) the drug itself is an antioxidant, can lower plasma cholesterol and LDL-c, HDL levels but also can drop by about 25%. Normal for patients with high cholesterol HDL. Its fewer side effects, mainly minor gastrointestinal reactions, it was observed that prolonged Q-T changes in question, thus disabling arrhythmia patients. Recent studies show that the antioxidant effect of the drug, can inhibit LDL oxidation, inhibition of atherosclerosis,You are not allowed to view links. Register or Login, which aroused wide interest, which has yet to be confirmed by further experimental and clinical. 2 2.1 General hypertriglyceridemia preferred fiber biological acid Xiaqi Yan (also known as fibrates) of these drugs include: Gemfibrozil (300m ~ piece, 300 ~ 600mg 2 times a day),You are not allowed to view links. Register or Login, bezafibrate (brand name will lipid-lowering, 2oo ~ / film, 200rag 3 times daily) and fenofibrate (brand name Lipanthyl. Add 0n-chip .200 mg day 1) and other mechanisms considered = these drugs inhibit the liver cells rig and very low density lipoprotein (VLDL) into Taiwan to enhance lipoprotein lipase activity, and promote liver TG and VLDL clearance related. Findings. These drugs on a non-competitive HMG-CoA reductase inhibition has a cholesterol-lowering effect. In addition to reducing the role of uric acid. The main side effects are gastrointestinal reactions (indigestion, flatulence, and diarrhea), elevated aminotransferases, blood urea nitrogen and creatinine increased, rash, easy to cause cholelithiasis, etc. = so when patients have liver and kidney dysfunction, bleeding tendency, or the smell of mutton Stone disabling disease. 2.2 nicotinic acid and its derivatives is a B vitamin niacin, the exact mechanism of its lipid-lowering is not clear, generally thought to reduce liver VLDL synthesis and increased VLDL decomposition, further reducing the level of serum rig and LDL, and solid reduced HDL decomposition, so that HDL increased (up to 5o%). The main side effects of skin flushing, itching, rash, gastrointestinal discomfort, abnormal liver function, increase blood uric acid, increased gouty arthritis. There are reports the average blood glucose concentration can increase 16%. Therefore, nicotinic acid in the treatment of diabetes,You are not allowed to view links. Register or Login, hyperlipidemia is not appropriate as first-line drugs, can only be used in patients with refractory hyperlipidemia and must be closely followed up. Pyrazine methotrexate (brand name music lipid levels, 250rr estrogen tablets .25 or 3 times a day), a nicotinic acid derivatives, with a strong and lasting, then stimulated lipoprotein lipase activity,You are not allowed to view links. Register or Login, promote decomposition and reduce VLDL synthesis of VLDL role. Can effectively lower plasma TG and cholesterol levels, and fewer side effects than nicotinic acid, was well tolerated in the treatment of diabetes, hyperlipidemia is a promising lipid-lowering drugs, but patients with diabetes can reduce the crown the risk of heart disease and the safety of long-term use, to be a large-scale clinical validation. 3 mixed hyperlipidemia of diabetes care business lipid mixed hyperlipidemia, lipid-lowering drugs in clinical use should be increased by reference to their lipid management drug selection conditions to homes. Increased if the main rig, the preferred fiber acid and its derivatives. If cholesterol-based, preferred delete G-c0A reductase inhibitors. If cholesterol, TG, LDL were significantly increased, then consider the joint care medication. There are two commonly used programs, one fibrates plus anion exchange resin, the second is a statin or anion-exchange resin plus niacin. These two programs, the case of small doses can increase drug efficacy, reduce side effects, but also to avoid the common anion exchange resins in therapy-induced hyperlipidemia high rig. Previous view that statins should be avoided associated with fibrate medications in Taiwan, the inherent risk of myopathy and rhabdomyolysis abroad in recent years about the possibility = of statins and fibrates together a number of medications in Taiwan homes new study shows that the two drugs not only effective and safe to use, but in the medication should be monitored during changes in muscle enzymes: (2000-09-14 Received l0 2OOO a repair of a pigsty 10): peptone Lei braided hair]