Renal nodules nodosa with autopsy case of multiple renal artery aneurysm _2122

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Renal nodules nodosa with autopsy case of multiple renal artery aneurysm
 
 
Dimension of the respiratory system involvement and pleurisy; circulatory system Yiyin acute and chronic bleeding disorder caused by circulating a large number of myocardial cells rupture,You are not allowed to view links. Register or Login, myocardial edema, myocardial interstitial inflammatory cell infiltration,You are not allowed to view links. Register or Login, resulting in instant death ventricular fibrillation. 3.2 Clinical characteristics of the PAN is a serious multi-system disease, due to medium-size along the artery can be touched and seen so called small nodules around the nodular artery inflammation. But in recent years recognized that vascular injury is not only involved the outer layer of the artery wall, but involvement of the arterial wall layers of necrotizing arteritis, leading to multiple aneurysms,You are not allowed to view links. Register or Login, thrombosis or infarction. Classic necrotizing nodular nodosa more common in the elderly, the violation of up to 85% of the kidney, the main lesions in the renal artery branches and leaves asking artery. Etiology is not fully understood,You are not allowed to view links. Register or Login, over the years that cause the allergic reactions in the pathogenesis play a major role. Course and prognosis of this disease depends on the scope of lesions involving the organ, severity and treatment or not. Whether the disease is acute or chronic, if not treated often leads to death,You are not allowed to view links. Register or Login, the survival rate <15% H. Occasionally, renal failure, glomerulonephritis combined treatment is effective, but no sign of urine and high blood pressure is dangerous, renal failure is the leading cause of death. Prompt diagnosis, early application of adrenal cortex hormones and immunosuppressive agents can greatly improve survival, 7-year survival rate of up to 80%. The disease recurrence rate was 40%, the average recurrence time of 33 months. 3.3 The differential diagnosis of the symptoms of the disease involves a number of different systems, identify key points are as follows: ① severe allergic purpura: the disease and the PAN can be rash, but severe allergic purpura rash more common in lower extremities, more short-lived; PAN rash often involve the whole body, a long time; ② chronic nephritis: As oliguria, hypertension and increased blood urea, PAN is often misdiagnosed as chronic nephritis alone, should be pay attention to; ③ Takayasu arteritis: Takayasu also to highlight the clinical manifestations of hypertension, such as arterial occlusive symptoms and also have fever, rash, arthritis, or erythrocyte sedimentation rate was faster, should be considered PAN; ④ systemic lupus erythematosus: systemic lupus erythematosus and renal injury in more than a typical rash , antinuclear antibody and lupus cytology positive, as identification. 3.4 PAN prognosis associated with renal involvement azotemia, acute renal failure and poor prognosis of malignant hypertension, cardiovascular involvement associated with coronary arteritis, myocardial infarction, heart failure and arrhythmias, patients can be life threatening. The most common PAN with renal involvement, mainly vascular damage to the kidneys, the kidney can cause multi-infarct acute renal failure, renal malignant hypertension, acute stage of the disease may have oliguria, and urine retention, but also a few months or the onset after a few years. In this case, coupled with severe chronic kidney ruptured renal artery aneurysm and renal acute renal failure, external bleeding, the symptoms despite symptomatic treatment was stable, the end result of multiple organ failure and cardiac involvement and death.