Fox Health: Autism risk could rise with air pollution, new study suggests

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Autism risk could rise with air pollution, new study suggests

Autism spectrum disorder and other neurodevelopmental disorders could be triggered by air pollution, a new study suggests. Researchers and other experts speak about the potential risk....                        ...                        ...                            ...You are not allowed to view links. Register or Login (ASD) and other neurodevelopmental disorders could be triggered by air pollution, including the type emitted in car exhaust, a new study suggested — though it had some limitations.......The review, led by Hebrew University of Jerusalem, analyzed multiple studies related to autism and cellular activity. The findings were published in the journal Brain Medicine.......The researchers focused on four specific types of particles that make up You are not allowed to view links. Register or Login: fine particulate matter (PM), nitrogen oxides (NO, NO2), sulfur dioxide (SO2) and ozone (O3).......You are not allowed to view links. Register or Login......They also investigated four different ways in which these particles could impact the fetus.......Those four ways were neuroinflammation, oxidative/nitrosative stress (an imbalance of free radicals and antioxidants that causes cell damage), epigenetic modifications (chemical changes to DNA) and disruptions to certain neurotransmitters, according to the study......."Increasing air pollution may significantly raise the risk of You are not allowed to view links. Register or Login, particularly ASD, due to gene-environment interactions," lead study author Haitham Amal, PhD, an associate professor at The School of Pharmacy at Hebrew University of Jerusalem, told Fox News Digital......."Key air pollutants — such as fine particulate matter, nitrogen oxides, sulfur dioxide and ozone — are implicated in triggering harmful processes in the brain, including neuroinflammation, oxidative stress and neurotransmitter imbalances," he added. ......You are not allowed to view links. Register or Login......The risk is highest during times of accelerated development, such as prenatal and You are not allowed to view links. Register or Login periods, according to Amal, who is also a visiting professor at Boston Children's Hospital within Harvard Medical School. ......"The brain starts developing at birth and continues to develop until the mid 20s," Georges Ghacibeh, M.D., a neurologist at Hackensack University Medical Center in New Jersey, told Fox News Digital. He was not involved in the study. ......"During the early years, from conception until about age 5, the brain undergoes the most changes and therefore is more susceptible to the impact of external factors," added Ghacibeh.......In a previous study published in 2023, the same research team found that nitric oxide (NO), which is one of the particles in You are not allowed to view links. Register or Login, is a "key pathological factor in autism," Amal noted. ......Ghacibeh agreed that air pollution could increase autism risk......."Chemicals inhaled by a You are not allowed to view links. Register or Login or a young child, if they enter the bloodstream and make it to the brain of the fetus or developing child, can affect various metabolic pathways, either by interfering directly with certain chemical reactions inside the cells, or by reducing the amount of oxygen delivered to the brain," he told Fox News Digital. ......This can interrupt the process of normal brain development, according to the doctor, causing brain cells to lose their normal function. ......"The mechanism would be similar to the effect of You are not allowed to view links. Register or Login ingested during pregnancy that can lead to developmental delay or autism in the child," Ghacibeh said.......Amal acknowledged that the study had some limitations......."The data is based on You are not allowed to view links. Register or Login," he said. "Extensive experiments in our labs should be done to validate and prove this connection."......You are not allowed to view links. Register or Login......Ghacibeh agreed, noting that epidemiological studies prove association but not causality. ......"In other words, if two phenomena occur simultaneously, such as high levels of air pollution and a rise in autism, this does not necessarily prove that one caused the other — it just means that both phenomena occurred at the same time. It is possible that additional, unknown factors might have played a role as well," he said.......Future research should aim to better understand pollution's effects on "genetically susceptible individuals" and to find ways to protect those at greatest risk, according to Amal......."This knowledge could inform You are not allowed to view links. Register or Login policies aimed at minimizing ASD risk from environmental pollutants," he added.......In the U.S., autism affects one in 36 children, or about 2.3%, as of 2024, according to statistics from the Centers for Disease Control and Prevention (CDC). ......This is an increase from one in 44 children two years ago.......Air pollution is also on the rise, affecting approximately 131.2 million people, or 39% of the U.S., as noted in the 2024 American Lung Association's State of the Air report. ......This is an increase of 11.7 million people from 2023. ......You are not allowed to view links. Register or Login......Living in areas with You are not allowed to view links. Register or Login — away from factories or airports, for example — could help to prevent potentially harmful effects of air pollution, Ghacibeh said......."Using good air filters, especially when you live in a higher-pollution environment, also helps mitigate those risks," he added.......You are not allowed to view links. Register or Login and limited exposure to smoking, alcohol and drugs also helps to promote optimal brain development and neurological health, according to Ghacibeh.......You are not allowed to view links. Register or LoginYou are not allowed to view links. Register or Login......The study was funded by grants from the U.S. Department of Defense (DoD) and the Eagles Autism Foundation, which raises funds for innovative research and care programs, according to its website, along with others.......Fox News Digital reached out to the Autism Foundation, Autism Spectrum Disorder Foundation and Autism Society for comment on the study....

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